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MOLECULAR GENETICS 681:502
Spring 2012 Tuesdays and Thursdays, 10-11:30 AM in the Waksman Institute Auditorium (Directions) Coordinator: Dr. Andrew Vershon, Waksman Institute, Rm. 234, 445-2905, vershon@waksman.rutgers.edu The main goal of this course is to expose students to the basic principals of genetics and genetic analysis. An underlying theme in the course is exposure to the advantages and genetic tools that are used in different model systems such as bacteria, bacteriophage, yeast, nematodes, Drosophila, plants, and mammals. The course design currently has a problem-based approach in which students are encouraged to understand how to do a genetic analysis and interpret results using practice problems and take home questions. There is no assigned textboook for this course. Faculty will post their notes and reading materials on the Sakai site for the course. For students that would like to review basic genetic concepts we suggest any undergraduate genetics textbook, such as Modern Genetic Analysis, Griffiths et al., Freeman & Co. Note that this text is available on-line for free at the NCBI Bookshelf. Students will be required to purchase i-clicker personal response units. New and used units are available in the RU bookstore or on the web. We will be using these in the first day of classes and your answers will be graded. |
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| Day | Date | Tentative Schedule of Topics | Instructor |
| Tues. | 1/17 | Basic Genetic Principals | Vershon |
| Thurs. | 1/19 | Bacterial Genetics - Conjugation, transformation, transduction | Vershon |
| Tues. | 1/24 | Bacterial Genetics – Bacteriophage, Deletion mapping | Vershon |
| Thurs. | 1/26 | Bacterial Genetics – Regulation - lac and trp Operon | Vershon |
| Tues. | 1/31 | Genetics of S. cerevisiae - Introduction | Vershon |
| Thurs. | 2/2 | Genetics of S. cerevisiae - Screens/selections | Vershon |
| Tues. | 2/7 | Genomics - DNA, protein, expression databases | Vershon |
| Thurs. | 2/9 | Genetics of S. cerevisiae - Screens/selections | Vershon |
| Tues. | 2/14 | Genetics of S. cerevisiae - Screens/selections examples | Vershon |
| Thurs. | 2/16 | Exam I: 9:00 AM- 11:45 AM UMDNJ West Lecture Hall |
Vershon |
| Tues. | 2/21 | Genetics of Drosophila - 1 | McKim |
| Thurs. | 2/23 | Genetics of Drosophila - 2 | McKim |
| Tues. | 2/28 | Genetics of Drosophila - 3 |
McKim |
| Thurs | 3/1 | Genetics of Drosophila - 3 | McKim |
| Tues. | 3/6 | Genetics of Arabidopsis - 1 |
Dong |
| Thurs. | 3/8 | Genetics of Arabidopsis - 2 |
Dong |
| Tues. | 3/13 | NO CLASS - SPRING BREAK | |
| Thurs. | 3/15 | NO CLASS - SPRING BREAK | |
| Tues. | 3/20 | Genetics of C. elegans- 1 | Rongo |
| Thurs. | 3/22 | Genetics of C. elegans- 2 | Rongo |
| Tues | 3/27 | Genetics of C. elegans- 3 | Rongo |
| Thurs. | 3/29 | Genetics of C. elegans- 4 | Rongo |
| Tues | 4/3 | Exam II 1:00 PM -4:00 PM UMDNJ Main Auditorium |
Dong / McKim / Rongo |
| Thurs. | 4/5 | Mammalian Genetics/Genomics - Mouse- 1 | Sahota |
| Tues | 4/10 | Mammalian Genetics/Genomics - Mouse- 2 | Sahota |
| Thurs. | 4/12 | Mammalian Genetics/Genomics - Mouse 3 |
Sahota |
| Tues | 4/17 | Mammalian Genetics/Genomics - Human |
Matise |
| Thurs. | 4/19 | Mammalian Genetics/Genomics- Human |
Matise |
| Tues | 4/24 |
Mammalian Genetics/Genomics - Genes and Disease |
Konsolaki |
| Thurs. | 4/26 |
Mammalian Genetics/Genomics - Genes and Disease | Konsolaki |
| Tues |
5/1 | Exam III 1:00 PM -4:00 PM UMDNJ West Lecture Hall
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Sahota / Konsolaki / Matise |
Last modified 1/16/12. Contact Andrew Vershon if you are having problems with the site